Research question
This study investigates a biomimetic copper–caffeic acid nanozyme and mechanisms associated with cuproptosis, pyroptosis and related cellular processes.
Omics approach
RNA-Seq compares expression after treatment. Pathway analysis explores lysosomal processes, copper-related responses, oxidative stress and cell death.
Mechanistic follow-up
Expression analysis complements material characterization and cellular and functional experiments. Omics findings generate mechanistic clues whose interpretation depends on the experimental system.
Paper and source
A Biomimetic Copper-Caffeic Acid Nanozyme Activates Cuproptosis and Pyroptosis by Mimicking the Neutrophil Enzymatic Cascade
Advanced Healthcare Materials
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